Lens autofluorescence has been found to correlate with diabetes. A number of companies have tried to develop instruments to use lens autofluorescence as a way to screen for Type 2 diabetes. There has been recent interest in using the fluorescent lifetimes of these fluorophores for diagnosis.
Selected References:
Kjer B, Larsen M, Bendison I, Binder C, Dalgaard P, Lund-Andersen H. Lens autofluorescence in diabetes compared with the level of glycosylated hemoglobin A1c. Acta Ophthalmol 182 (Suppl) 28:100 (1987). PubMed
Karumanchi DK, Gaillard ER, Dillon J. Early Diagnosis of Diabetes through the Eye. Photochem Photobiol 91(6):1497-504 (2015). PubMed