Tear Flow

Benedetto DA, Clinch TE, Laibson PR. In vivo observation of tear dynamics using fluorophotometry. Arch Ophthalmol 102:410-412 (1984). PubMed

Chang SW, Chang CJ. Delayed tear clearance in contact lens associated papillary conjunctivitis. Curr Eye Res 22(4):253-7 (2001). PubMed

Chen FS, Maurice DM. The pH in the precorneal tear film and under a contact lens measured with a fluorescent probe. Exp Eye Res 50:251-259 (1990). PubMed

Chen T, Ward DA. Tear volume, turnover rate, and flow rate in ophthalmologically normal horses. Am J Vet Res 671-6 (2010). PubMed

Craig JP, Tomlinson A, Patterson NS, Reid VE, McFadyen AK. Tear production measurement, basal or reflex assessment? Adv Exp Med Biol 506(Pt B):1159-63 (2002).

Eliason J, Maurice DM. Staining of the conjunctiva and conjunctival tear film. Brit J of Ophthalmol. 74:519-522 (1990). PubMed

Eter N, Gobbels M. A new technique for tear film fluorophotometry. Br J Ophthalmol 86(6):616-9 (2002). PubMed

Eter N, Schuller H. External beam radiotherapy for age-related macular degeneration causes transient objective changes in tear-film function. Graefes Arch Clin Exp Ophthalmol 239(12):923-6 (2001). PubMed

Furukawa RE, Polse KA. Changes in tear flow accompanying aging. Am J Optom Physiol Opt 52:69-74 (1978). PubMed

Garaszczuk IK, Montes Mico R, Iskander DR, Expósito AC. The tear turnover and tear clearance tests – a review. Expert Rev Med Devices. 15(3):219-229 (2018). PubMed

Garcia MS, De La Rosa MG, Moreno CM, Barreto LP, Martin CG. Determination of basal lacrimal flow in facial paralysis through fluorophotometry. New Trends Ophthal 3:193.

Garcia MS, De La Rosa MG, Moreno CM, Sierra MG, Barreto LP. Determination by fluorophotometry of the influence of pilocarpine and timolol on the lacrimal flow. New Trends Ophthal 3:177.

Goebbels M. Tear secretion and tear film function in insulin dependent diabetics. Br J Ophthalmol 84(1):19-21 (2000). PubMed

Goebbels M, Selbach J, Spitznas M. Effect of eledoisin on tear volume and tear flow in humans as assessed by fluorophotometry Graefes Arch Clin Exp Ophthalmol 229:549- (1991). PubMed

Gonzalez de la Rosa M, Serrano Garcia M, Cardona Guerra P, Hernandez CC. (Valoration of lacrimal production. A new fluorophotometric method.) Arch Soc Canaria Oftalmol (Spain) 6:33-39 (1981).

Jordan A, Baum J. Basic tear flow. Does it exist? Ophthalmology 87:920-930 (1980). PubMed

Keijser S, van Best JA, Van der Lelij A, Jager MJ. Reflex and steady state tears in patients with latent stromal herpetic keratitis. Invest Ophthalmol Vis Sci. 43(1):87-91 (2002). PubMed

Ko L, Maurice D, Ruben M. Fluid exchange under scleral contact lenses and wearing time. Brit. J. Ophthalmol. 54:486-489 (1970). PubMed

Kono A, Yokoi N, Komuro A, Kinoshita S. Fluorophotometric evaluation of tear turnover under hard contact lens. J Jpn Contact Lens Soc 36:175- (1994).

Kuppens EVMJ, Stolwijk TR, de Keizer RJW, van Best JA. Basal tear turnover and topical timolol in glaucoma patients and healthy controls by fluorophotometry. Inv Ophthalmol Vis Sci 33:3442- (1992). PubMed

Macdonald EA, Maurice DM. The kinetics of tear fluid under the lower lid. Exp Eye Res 53: 421-426 (1991). PubMed

Mathers WD, Lane JA, Zimmerman MB.  Tear film changes associated with normal aging.   Cornea 15:229-234 (1996). PubMed

Mathers WD, Stovall D, Lane JA, Zimmerman MB, Johnson S.  Menopause and tear function: the influence of prolactin and sex hormones on human tear production.   Cornea 17:353-358 (1998). PubMed

Maurice DM. The tonicity of an eye drop and its dilution by tears. Exp Eye Res 11:30-33 (1971). PubMed

McCulley JP, Shine WE, Aronowicz J, Oral D, Vargas J. Presumed hyposecretory/hyperevaporative KCS: tear characteristics. Trans Am Ophthalmol Soc 101:141-52; discussion 152-4 (2004). PubMed

McNamara NA, Polse KA, Brand RJ, Graham AD, Chan JS, McKenney CD. Tear mixing under a soft contact lens: effects of lens diameter. Am J Ophthalmol 127(6):659-65 (1999). PubMed

Meadows DL, Paugh JR, Joshi A, Mordaunt J. A novel method to evaluate residence time in humans using a nonpenetrating fluorescent tracer. Invest Ophthalmol Vis 43(4):1032-9 (2002). PubMed

Muntz A, Subbaraman LN, Sorbara L, Jones L. Tear exchange and contact lenses: a review. J Optom 8(1):2-11 (2015). PubMed

Occhipinti JR, Mosier MA, LaMotte J, Monji G. Fluorophotometric measurement of human tear turnover rate. Curr Eye Res 7:995-1000 (1988). PubMed

Paugh JR, Stapleton F, Keay L, Ho A. Tear exchange under hydrogel contact lenses: methodological considerations. Invest Ophthalmol Vis Sci 42(12):2813-20 (2001). PubMed

Pearce EI, Keenan BP, McRory C. An improved fluorophotometric method for tear turnover assessment. Optom Vis Sci 78(1):30-6 (2001). PubMed

Polse KA. Tear flow under hydrogel contact lenses. Invest Ophthalmol Vis Sci 18:409-413 (1979). PubMed

Sahlin S, Chen E.  Evaluation of the lacrimal drainage function by the drop test.   Am J Ophthalmol 122:701-708 (1996). PubMed

Sang NM, Maurice DM. Poor mixing of microdrops with the tear fluid reduces the accuracy of tear flow estimates by fluorometry. Curr Eye Res 14:275-280 (1995). PubMed

Sebbag L, Allbaugh RA, Wehrman RF, Uhl LK, Ben-Shlomo G, Chen T, Mochel JP. Fluorophotometric Assessment of Tear Volume and Turnover Rate in Healthy Dogs and Cats. J Ocul Pharmacol Ther 35(9):497-502 (2019). PubMed

Sebbag L, Kirner NS, Allbaugh RA, Reis A, Mochel JP. Kinetics of Fluorescein in Tear Film After Eye Drop Instillation in Beagle Dogs: Does Size Really Matter? Front Vet Sci 6:457 (2019). PubMed

Sebbag L, Soler EA, Allbaugh RA, Mochel JP. Impact of acute conjunctivitis on ocular surface homeostasis in dogs. Vet Ophthalmol 23(5):828-833 (2020). PubMed

Shimizu A, Yokoi N, Nishida K, Kinoshita S, Akiyama K. Fluorophotometric measurement of tear volume and tear turnover rate in human eyes. J Jpn Ophthalmol Soc 97:1047- (1993). PubMed

Stodmeister R, Kessler KF, Schlorer J. Tear film break-up time with different stains. Klin Monatsbl Augenheilkd 183:110-114 (1983).

Tang NE, Zuure PL, Pardo RD, de Keizer RJ, Van Best JA. Reflex lacrimation in patients with glaucoma and healthy control subjects by fluorophotometry. Invest Ophthalmol Vis Sci 41(3):709-14 (2000). PubMed

Tomlinson A, Blades KJ, Pearce EI. What does the phenol red thread test actually measure? Optom Vis Sci 78(3):142-6 (2001). PubMed

van Best JA, Kuppens EVMJ, Stolwijk TR, de Keizer RJW. Topical timolol and basal tear turnover in glaucoma by fluorophotometry. Invest Ophthalmol Vis Sci 32 (Suppl.):989 (1991).

Verhoeyen MH, Khalil HA, van Best JA. Fluorophotometric determination of the basal tear production Supp Title: Abstracts from the 183rd Congress… Int Ophthalmol 13:472 (1989).

Wojtowicz JC, Butovich I, Uchiyama E, Aronowicz J, Agee S, McCulley JP. Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of
an omega-3 supplement for dry eye. Cornea 30(3):308-14 (2011). PubMed

Xu KP, Tsubota K. Correlation of tear clearance rate and fluorophotometric assessment of tear turnover. Br J Ophthalmol 79:1042- (1995). PubMed

Yamada M, Kawai M, Mochizuki H, Hata Y, Mashima Y.  Fluorophotometric measurement of the buffering action of human tears in vivo.  Curr Eye Res 17:1005-1009 (1998). PubMed


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